Pilot use-case – research demonstrator
Aggressive clear cell renal carcinoma risk at 24 months (10/100/400 genes)
High-dimensional gene expression modeling with robustness and stability across dimensionalities.
Research-only disclaimer
These demonstrator use cases are provided for scientific research and exploration purposes only.
They do not constitute medical diagnosis, clinical decision support, or treatment recommendation.
Ethical and Regulatory Note
Read the cross-cutting note →Research question
How does tumor gene expression dimensionality influence the modeling of aggressive disease evolution in clear cell renal carcinoma, in a research setting?
Explicit exclusions (non-negotiable)
- No treatment recommendation
- No patient-level decision support
Data structure (illustrative)
- Gene expression vectors (10, 100, 400 genes)
- Outcome: aggressive vs non-aggressive evolution
- Time horizon: 24 months
Modeling concepts (demo-level)
- High-dimensional risk modeling
- Overfitting & feature selection risk
- Stability across dimensionalities